Please do not use the "Online - Download Configuration" menu option from inside the PCB "PROFIBUS - PDPMV1" configuration window. If you do this, it will lock up PCB, requiring you to shut it down and restart it to clear the error.
Instead, exit the "PROFIBUS -PDPMV1" configuration window, and use the "Project - Module - Download From PC to Device" option from the Main PCB window. This should work every time without locking up PCB.